서브 비주얼
컨텐츠
Mirae biotechCHITOSAN
[History]
1811 – Braconnot, a French professor of natural history, discovered fungine in mushrooms and became the beginning of Chitin.
1823 – Odier, a French scientist, discovered the same material isolated from elytra of May beetles. 'Chitin' originated from the Greek word of Chiton meaning tunic.
A new substance was obtained by deacetylation of Chitin. 'Hoppe-Seyler', a scientist, named it Chitosan.
It was relatively difficult to use Chitin rather than cellulose, because of its hard structure. However, it has been highlighted sine the research was conducted by Ministry of Education, Culture, Sports, Science and Technology in 1985. 'Fuji Bio Co., Ltd' released the world's first chitosan health food in Japan in1986.
In Korea, chitosan was registered as the natural food additive in 1995. Chitosan processed foods and chitooligosaccharide processed foods are separately announced in April, 2000. They were classified as health functional foods in 2004.
[Functionality]
Blood pressure reduction effects
: Amino group (+ charge) of Chitosan excretes chloride ion by interacting with chloride ion (- charge), which raises blood pressure. Blood pressure reduction effects
Cholesterol lowering effects
: Chitosan with molecular weight of 5,000 or more has the functionality. It lowers cholesterol levels by interacting with the bile acid produced using cholesterol in the liver.
Effects of improving liver functions and lowering blood pressure
N-acetylglucosamine or D-glucosamine, degradation products of Chitin and Chitosan, normalizes the actions of insulin by expanding the capillaries in the entire body through vagus nerves in the liver and increasing pH.
Antibacterial effects
Polymer has large effects to inhibit the growth of bacteria and fungi. Antibacterial effects are expressed by the amino group (+ charge) of Chitosan.
Anti-cancer effects caused by enhancement of the immune system
: Even if it has been found that derivatives of Chitin and Chitosan produce antibodies in the immune system, killer T cells, natural killer cells, induce activated helper T cells, and activate macrophage with interferon, it has physical limitations in which the polymers are not dissolved in water. On the other hand, chitinoligosaccharides enhance the immune system by activating the nonspecific defense mechanism against infection through phagocyte.
Chitosan specification
| Product name | Appearance | Total Glucosamine (%) |
Moisture | pH | Total Microorganism |
|---|---|---|---|---|---|
| Chitosan | CONFORME | 80% | less than 10% | - | NEGATIVE |
| Chitosan Water soluble | 80% | less than 10% | 5~7.5 | NEGATIVE |
Chitooligosaccharide
| Product name | CHITO OLIGO-SACCHARIDE 20 | CHITO OLIGO-SACCHARIDE 50 | CHITO OLIGO-SACCHARIDE 65 | CHITO OLIGO-SACCHARIDE 70 | CHITO OLIGO-SACCHARIDE 80 |
|---|---|---|---|---|---|
| Appearance | CONFIRME | ||||
| Content (%) | 20% | 50% | 65% | 70% | 80% |
| Insolubles | INSOLUBLE | INSOLUBLE | INSOLUBLE | INSOLUBLE | INSOLUBLE |
| pH | 5~7.5 | 5~7.5 | 5~7.5 | 5~7.5 | 5~7.5 |
| Moisture | less than 10% | less than 10% | less than 10% | less than 10% | less than 10% |
| Viscosity | 1~5 | 1~5 | 1~5 | 1~5 | 1~5 |
| Total Micro organism |
NEGATIVE | NEGATIVE | NEGATIVE | NEGATIVE | NEGATIVE |
| Heavy metals | less than 10ppm | less than 10ppm | less than 10ppm | less than 10ppm | less than 10ppm |
